Kawasaki Disease (KD) Kawasaki disease (KD) is a childhood illness that causes vasculitis (inflamed blood vessels). KD is more common in children younger than 5 years old. KD occurs more…
Juvenile Arthritis Juvenile idiopathic arthritis (JIA) is chronic arthritis that affects approximately 1 in every 1,000 children. JIA affects children less than 16 years of age. It is not usually…
Inflammatory Myopathies Inflammatory myopathies are muscle diseases caused by inflammation. They are autoimmune diseases where the body’s immune system attacks its own muscles by mistake. The most common inflammatory myopathies…
IgG4-Related Disease (IgG4-RD) IgG4-related disease (IgG4-RD) is an immune-mediated condition, meaning that it involves the occurrence of disease in organs as the result of an abnormally regulated immune system. The…
Hypermobility Syndrome (Juvenile) In hypermobility syndrome, a child’s joints move past the normal range of motion. Children with hypermobile joints are often called “double" or "loose" jointed. Hypermobile children may…
Hyperimmunoglobulin D Syndrome (HIDS) / Mevalonate Kinase Deficiency (MKD) (Juvenile) Mevalonate kinase deficiency (MKD), formerly called hyperimmunoglobulin-D syndrome (HIDS), is a rare, genetic disease that causes recurrent episodes of fever…
HIV & Rheumatic Disease People with HIV infection and acquired immunodeficiency syndrome (AIDS) often have problems in their joints, muscles, and bones. People may notice these problems before they know…
Henoch Schönlein Purpura (HSP) Henoch Schönlein Purpura (HSP) is a type of vasculitis, which means inflammation of the blood vessels. The exact cause of HSP is unknown and there is…
HCV & Rheumatic Disease Chronic Hepatitis C virus (HCV) infection is the leading cause of liver failure and the need for liver transplant. The main way HCV spreads today is…
Granulomatosis with Polyangiitis (Wegener's) Granulomatosis with polyangiitis (GPA), formerly called Wegener’s granulomatosis, is a rare blood vessel disease. It’s a type of vasculitis, or inflammation of the blood vessels, specifically…
Glucocorticoid-Induced Osteoporosis Glucocorticoid-Induced Osteoporosis (GIO) is a condition in which people who take medicines called glucocorticoids develop osteoporosis, which means weakening of the bones. Treatment with glucocorticoids for inflammatory arthritis or…
Giant Cell Arteritis Giant cell arteritis causes inflammation of certain arteries, especially those near the temples. The most common symptoms of giant cell arteritis are head pain and tenderness — often…
Fibromyalgia Fibromyalgia is a chronic condition that causes widespread pain. It affects 2-4% of people, usually women. People who have other rheumatic diseases are at higher risk of having fibromyalgia.…
Familial Mediterranean Fever Familial Mediterranean Fever (FMF) is a non-infectious genetic disorder manifested by episodic fevers typically accompanied by pain in the abdomen, joints, or chest. FMF is caused by…
Dermatomyositis (Juvenile) Juvenile dermatomyositis (JDM) is a disease in which a child’s immune system primarily attacks the skin and muscles or blood vessels. The cause of JDM remains unknown to…